AC Milan vs Manchester United; Trust Devils to Deliver on Thursday night Updated for December 2025

18/03/2021 | Categories: Football betting | Published by: Andy Nelson

Updated: 13th December 2025

2020-21 UEFA Europa League Round of 16 second-leg preview: AC Milan vs Manchester United – San Siro, Milan – Thursday, March 18, 2021 – 20:00 hrs BST

Score in first leg 1-1

AC Milan vs Manchester United Prediction

Correct Score betting Advice;

Manchester United to qualify: 20/33

odds quoted are subject to change and were correct as of 18/03/2021.

AC Milan vs Manchester United Preview

It's a do-or-die for AC Milan and Manchester United at San Siro on Thursday night as both teams fight it out for a place in the Round of 16 of the 2020-21 Europa League. The two sides played out a 1-1 draw in the first leg at Old Trafford, with Amad Diallo's 50th minute header being cancelled out by Milan's Simon Kjaer deep inside injury time in the 92nd.

Stefano Pioli's AC Milan have slipped from a dominant first spot they held on the Serie A table till early-February to a distant second to city rivals Inter-Milan to whom they are behind by as much as 9 points after 27 games.

The Milanese club have just two wins and three losses to show from their last six domestic outings and with defeats to Juventus, Atalanta, Inter Milan and Napoli at the San Siro in 2021 itself, there will be incredible pressure on the Rossoneri to deliver at the home venue on March 18th.

Ole Soksjaer's Red Devils are unbeaten in their last 13 matches across all competitions and with some of their key players expected to return to the squad, they should feel confident going into Thursday's game.

Last 6 Matches Form

AC Milan form guide: L-W-D-W-D-L

Manchester United form guide: W-D-D-W-D-W

Team news

The good news for the AC Milan is that Ante Rebic, Hakan Calhanoglu and Theo Hernandez who featured in the weekend game against Napoli are all expected to start on Thursday. Still doubtful are Zlatan Ibrahimovic and Alessio Romagnoli who could feature in the first leg too. Mario Mandzukic and Ismael Benancer are sidelined through injuries as well.

Solskjaer has revealed that United might be able to welcome Paul Pogba back into the side after having spent some time on the sidelines. Donny van de Beek and Edinson Cavani still seem doubtful while Phil Jones and Juan Mata are both ruled out.

AC Milan probable starting XI in a 4-2-3-1 formation: Gianluigi Donnarumma (goal); Theo Hernandez, Fikayo Tomori, Simon Kjaer, Davide Calabria; Franck Kessie, Sandro Tonali; Hakan Calhanoglu, Rade Krunic, Alexis Saelemaekers; Rafael Leao

Manchester United probable starting XI in a 4-2-3-1 formation: Dean Henderson (goal); Aaron Wan-Bissaka, Harry Maguire, Victor Lindelof, Luke Shaw, Scott McTominay, Fred, Bruno Fernandes, Anthony Martial, Marcus Rashford; Mason Greenwood

The late goal given away at Old Trafford may come back to haunt United, but they simply have too much power not to see this one through. With a depleted Milan side in poor recent form and United's excellent track record on their travels, it's hard not to see the visitors from England qualify for the next stage.

Selected Bookmaker odds

The latest AC Milan vs Manchester United bookmaker odds quoted below have been taken from the leading football betting sites online and are subject to change.

Manchester United to qualify: 8/13
AC Milan to qualify: 5/6