Looking shaky for Reds against 13 times Champions Updated for December 2025

13/04/2021 | Categories: Football betting | Published by: Andy Nelson

Updated: 12th December 2025

2020-21 UEFA Champions League quarter-final second-leg preview: Liverpool v Real Madrid – Anfield – Wednesday, 14 April 2021 – 20:00 hrs. BST

Liverpool v Real Madrid Preview

Liverpool will be hoping for a miracle as they try to overturn a 1-3 deficit from the first leg of their quarter-finals tie against Real Madrid on Wednesday at Anfield.

Both sides are going into the Anfield clash with domestic wins – Real edging 2-1 past Barcelona in an El Classico clash on Saturday while Liverpool managed to squeeze past Aston Villa in a Premier league game by a similar margin on the same night.

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[su_panel color=”#000000″ border=”4px solid #16a012″ shadow=”3px 3px 2px #eeeeee” radius=”4″]The Reds' three wins on the trot is probably their best phase in an otherwise dismal season while Madrid's five back-to-back La Liga wins have helped them to come within a point of leaders Atletico Madrid.[/su_panel]

Recent Form

Liverpool Champions League form: LWDWWL

Liverpool form across all competitions: LWWWLW

Real Madrid Champions League form: WLWWWW

Real Madrid form across all competitions: WWWWWW

Team news

With Virgil van Dijk, Joe Gomez and Joel Matip still out on a long-term basis for Liverpool, it will be upto the likes of the inexperienced Nathaniel Phillips and Ozan Kabak to hold things at the back and deal with the attacking battery of the visitors.

Midfielder Jordan Henderson is not yet fit enough to make a comeback while Curtis Jones who sat out in the Aston Villa game as a precaution owing to a muscular problem, could find himself in the squad this week. James Milner or Thiago Alcantra are thus in with a chance for starts in the midfield space in the absence of Henderson.

For Real Madrid, defensive mainstays Sergio Ramos and Dani Carvajal will miss out as they did in the first leg owing to calf and hamstring injuries respectively. Center-back Raphael Varane is still sick while one more casualty in the defensive department is Lucas Vazquez with a cruciate ligament sprain sustained during Saturday's El Classico.

Central midfielder Federico Valverde also joined the list of the injured after the clash with Barcelona while the still-not-fit ace forward Eden Hazard will have to spend time on the sidelines.

Liverpool possible starting XI in a 4-3-3 formation:

Alisson (goal); Alexander-Arnold, Phillips, Kabak, Robertson; Fabinho, Wijnaldum, Milner; Salah, Jota, Mane

Real Madrid possible starting XI in a 4-3-3 formation:

Courtois (goal); Odriozola, Nacho, Militao, Mendy; Casemiro, Kroos, Modric; Asensio, Benzema, Vinicius Jr

Wednesday night's second leg at Anfield will be the eighth meeting between these two sides with Liverpool having won thrice and Real Madrid four.

[su_panel color=”#000000″ border=”4px solid #16a012″ shadow=”3px 3px 2px #eeeeee” radius=”4″]Karim Benzema's four goals in this fixture makes him a threat as he could well add a fifth. Liverpool's only succour could come from an absolutely depleted Real defense in the absence of Ramos & co which their attackers will look to exploit.[/su_panel]

But with a two-goal deficit and defensive frailties of their own, Jurgen Klopp's Reds will have to hope for a miracle against the world-class attack of the thirteen-time champions.

Real Madrid to qualify: 2/9
Liverpool to qualify: 3/1