Red Devils have an edge over struggling Southampton in tonight’s Manchester United vs Southampton clash Updated for July 2025

Updated: 17th July 2025

2020-21 EPL Preview: Manchester United vs. Southampton – Old Trafford – Tuesday, February 2nd, 2021 – 20:15 hrs BST

Manchester United vs Southampton Prediction

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Manchester United vs Southampton Preview

Ole Solksjaer’s United will be looking to find their mojo back after collecting just one point from their last two fixtures. The Red Devils will be looking to recover from the shock of having lost to bottom-placed Sheffield and a goalless draw against Arsenal following that.

Southampton on the other hand will be coming into the Old Trafford clash on the back of three straight losses that has seen them drop to the 11th position on the table and 12 points adrift of their 2nd-placed rivals.

Manchester United Premier League form: W/W/D/W/L/D

Southampton Premier League form: D/D/W/L/L/L

As for team news, United will be without the services of out-of-favour Phil Jones and Marcos Rojo with the latter possibly exiting the club before Tuesday's game. Scott McTominay looks doubtful after he walked out midway through the game against Arsenal with stomach cramps.  Eric Bailly and Nemanja Matic could be in line for starts while Anthony Martial could return in the striker's role. Edinson Cavani, who played the entire ninety minutes in the drawn fixture against the Gunners could be rested amidst a busy schedule of games.

As for the Saints, Nathan Tella, Mohammed Salisu and Michael Obafemi and William Smallbone are still injured with key defenders Jannik Vestergaard and Kyle Walker-Peters joining the list. Coach Ralph Hasenhuttl will stick to the same eleven that lost 0-1 to Aston Villa last week with Yan Valery potentially starting at the back.

Manchester United probable starting XI:

De Gea (goal); Wan-Bissaka, Bailly, Maguire, Shaw; Fred, Matic; Pogba, Fernandes, Rashford; Martial

Southampton probable starting XI:

McCarthy (goal); Valery, Bednarek, Stephens, Bertrand; Walcott, Romeu, Ward-Prowse, Armstrong; Adams, Ings

This could be a very tough outing for United given their shaky performances at home and the Saints' ability to overcome any side at their best despite their poor recent form. But a desperate United could be expected to collect three points from Tuesday night's encounter at Old Trafford. A draw cannot be ruled, too.

Manchester United vs Southampton betting Odds

• Manchester United to win: 1/2
• Southampton to win: 6/1
• Draw: 10/3

Correct score

• Manchester United 2-0: 15/2
• Draw 1-1: 15/2
• Manchester United 2-1: 8/1 (predicted scoreline)
• Manchester United 1-0: 8/1
• Manchester United 3-1: 12/1
• Draw 0-0: 12/1
• Draw 2-2: 16/1
• Southampton 2-1: 20/1
• Southampton 1-0: 20/1
• Manchester United  3-2: 25/1
• Southampton 2-0: 40/1

Anytime goalscorer

(SkyBet odds)

• Bruno Fernandes: 19/20
• Edinson Cavani: 21/20
• Marcus Rashford: 13/8
• Anthony Martial: 7/4
• Danny Ings: 7/4
• Mason Greenwood: 11/5
• Paul Pogba: 3/1
• Che Adams: 3/1
• James Ward-Prowse: 15/4

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